|
HS Code |
341881 |
| Cas Number | 67-03-8 |
| Chemical Name | Thiamine Hydrochloride |
| Molecular Formula | C12H17ClN4OS |
| Molecular Weight | 337.85 g/mol |
| Appearance | White or almost white crystalline powder |
| Solubility In Water | Freely soluble |
| Ph Of 2 Percent Solution | 2.7 – 3.4 |
| Melting Point | 248°C (decomposes) |
| Dc Grade Use | Direct compression in tablet manufacturing |
| Odor | Characteristic, faint |
| Shelf Life | Typically 24 months |
| Packaging | Usually packed in 25 kg fiber drums |
| Synonyms | Vitamin B1 Hydrochloride |
As an accredited Thiamine Hydrochloride DC Grade factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Thiamine Hydrochloride DC Grade is packed in 25 kg fiber drums with inner polyethylene liners, ensuring product safety and freshness. |
| Container Loading (20′ FCL) | 20′ FCL (Full Container Load) for Thiamine Hydrochloride DC Grade: Securely packed, 8-10 metric tons per container, bulk or carton boxes. |
| Shipping | Thiamine Hydrochloride DC Grade is securely packed in fiber drums or HDPE containers, each with double-layer polyethylene liners to maintain product integrity. Standard packaging sizes are 25 kg net weight. Shipments are handled carefully to avoid moisture, extreme temperatures, and contamination, ensuring compliance with international safety and transport regulations. |
| Storage | Thiamine Hydrochloride DC Grade should be stored in a tightly closed container, protected from light, heat, and moisture. Store in a cool, dry, and well-ventilated area, ideally at room temperature (below 25°C). Keep away from incompatible substances and sources of ignition. Ensure proper labeling and adherence to local safety regulations to maintain product quality and stability. |
| Shelf Life | Thiamine Hydrochloride DC Grade typically has a shelf life of 24 months when stored in a cool, dry, and well-sealed container. |
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Purity 99%: Thiamine Hydrochloride DC Grade with purity 99% is used in direct compression multivitamin tablets, where it ensures high potency and uniform nutrient distribution. Particle Size 100 μm: Thiamine Hydrochloride DC Grade with particle size 100 μm is used in effervescent tablet production, where it enables rapid disintegration and dissolution rates. Moisture Content <2%: Thiamine Hydrochloride DC Grade with moisture content less than 2% is used in chewable vitamin tablets, where it provides improved product stability and shelf life. Flowability Index >95: Thiamine Hydrochloride DC Grade with flowability index over 95 is used in high-speed tablet presses, where it supports consistent tablet weight and reduced machine downtime. Bulk Density 0.55 g/cm³: Thiamine Hydrochloride DC Grade with bulk density of 0.55 g/cm³ is used in nutritional premix blends, where it facilitates homogeneous mixing and ease of handling. Stability Temperature 50°C: Thiamine Hydrochloride DC Grade with stability temperature of 50°C is used in heat-processed nutraceuticals, where it maintains vitamin integrity during production. Loss on Drying <1%: Thiamine Hydrochloride DC Grade with loss on drying less than 1% is used in sports nutrition tablets, where it enhances physical and chemical stability during storage. Compressibility Index 12%: Thiamine Hydrochloride DC Grade with compressibility index of 12% is used in high-dose vitamin supplement tablets, where it improves tablet formation and reduces friability. Assay 98-102%: Thiamine Hydrochloride DC Grade with assay range 98-102% is used in pharmaceutical-grade vitamin formulations, where it assures label claim compliance and dose accuracy. Uniform Particle Distribution: Thiamine Hydrochloride DC Grade with uniform particle distribution is used in combination vitamin tables, where it allows for consistent blending and tablet homogeneity. |
Competitive Thiamine Hydrochloride DC Grade prices that fit your budget—flexible terms and customized quotes for every order.
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Every day on our production line, delivering consistent Thiamine Hydrochloride DC Grade challenges our team and pushes our expertise forward. Over years of manufacturing synthetic vitamins for food, supplements, and pharmaceuticals, we have learned how minor changes in physical properties affect high-throughput applications and customer outcomes. The direct compression (DC) variant of Thiamine Hydrochloride started as a response to practical pain points—high dust, variable flow, complex blending—that our partners in tableting and premix operations described during visits and feedback sessions.
In our facility, Thiamine Hydrochloride DC Grade carries the chemistry of vitamin B1 (thiamine HCl), paired with specific flow and compression properties that only careful dry blend adjustments and precise quality controls can achieve. Model numbers differentiate DC grade from other options, but in everyday use, what matters most is performance at scale, batch after batch. Each granule offers a free-flowing texture with particle size parameters suited to automatic presses. Oversized, sticky, or dusty powders directly translate to equipment downtime and inconsistent dosing; we see these differences play out in our clients’ OEE (overall equipment effectiveness) data and customer returns.
Manufacturers and formulators have plenty of experience with traditional thiamine HCl powders. These legacy lots serve in diverse nutrition and fortification programs, particularly where cost and purity are the only priorities. Some plants lean on them for batch blends or wet granulation processes where later steps can correct texture and flow. Our DC Grade doesn’t compete by purity alone—it stands up to direct compression’s unforgiving demands.
Direct compression calls for a vitamin that blends quickly, sticks together under pressure, and doesn’t segregate during transfer. Regular powder, straight off synthesis, demands special handling, extra chemicals, or double blending—costs that reach far past price per kilo. Process observation here at the factory taught us that to really support tablet operators, DC Grade needs more than just micronized particles; it also absorbs less ambient moisture, resists caking, and runs with minimal dust during transfer. In each lot, we test not only for chemical assay but also for flow time, bulk density, and compressibility. These quality points shift the difference from theoretical to operational reliability.
Operators share plenty of stories about common pitfalls with ordinary grades: stopped presses, weight variation, broken punches. Each of these traces back to basic material handling and consistency. By steering our DC process towards controlled physical modifications—granulation with safe binders, precise particle sizing, and reduced fines—we enable a pace of work and level of performance that legacy pharmaceutical standards demand, but everyday supplement lines benefit from just as much.
Formulators work closely with the physical properties of every raw material, not just the vitamin content. Those at major contract manufacturers repeatedly tell us that saving steps in mixing and blending makes a measurable difference at commercial scale. Too often, generic thiamine powder requires a series of pre-mix and milling steps just to play nicely with excipients or actives. Each intervention invites risk—segregation, loss, or contamination.
DC Grade was meant to reduce these headaches. We were early adopters of binder technologies allowing thiamine powder to form cohesive granules suitable for direct introduction to tableting blenders. Instead of sticking in the pre-mix stage or clogging screens, our DC Grade pours into the mixer smoothly, with particle-size distribution targeting 100-500 microns to balance compression and disintegration. Our QA data shows that this level of control lets tableting lines achieve target hardness and friability specs without punching up lubricant or disintegrant levels.
Stepping away from one-size-fits-all, we don’t batch blend by chance; our QC checks particle flow through small-scale replicas of real buyer equipment, catching issues in lab-scale compression and simulated transport before shipping a single drum. This step makes us confident sending our product not just to domestic supplement plants, but also to global formulators working with tight spec requirements for EU, US, or APAC regulations.
Most people in chemical sales talk about purity, but on the shop floor, the truth is that reliability starts with how a product pours from the bag and how it behaves under pressure. Even the highest-assay thiamine HCl becomes a liability if it bridges in the hopper, segregates during mixing, or simply dusts too much to keep machines clean.
We have spent time on production floors around the world—Asia, Europe, North America—where operators care less about marketing specs and more about yesterday's downtime. Our thiamine hydrochloride DC grade was developed to reflect those frontline needs. The idea sounds simple: take the base USP or EP grade active, use food-safe granulating binders, and build a compressible grade that won’t slow down high-speed tablet lines. Actually doing it right means tracking small things: lot-to-lot consistency, bulk density in the Goldilocks zone, particle breakdown on real tablet presses, and absence of capping or lamination. These aren't just numbers on a page but solutions developed by making and breaking thousands of test tablets year after year.
In recent years, we got requests from clients operating continuous manufacturing setups, especially in the US and EU, who reported that our DC Grade reduced line stoppages by roughly 15-20% compared to their incumbent thiamine sources. Plant managers see an immediate impact—less mess in feeders, lower cross-contamination cleaning, and fewer costly recalls due to tablet weight deviation.
Most traders sell thiamine hydrochloride based only on assay and price, often unaware of how sensitive modern automated lines are to minor particle and flow differences. We manufacture from the ground up, so we’re called when unusual GMP or scale-up issues surface. Working closely with QA and production means we don’t just push product but investigate how it interacts with tableting excipients—microcrystalline cellulose, dicalcium phosphate, stearates. We’ve remade some lots at our own expense when customer tablets picked up unwanted color or stuck to dies, determined to solve not hide the problem.
Direct compression grade takes more investment in plant and process validation than generic powder. Our DC lines run in closed systems to minimize dust, with built-in sieving and metal detection. Automating these stages keeps each lot within narrowly defined flow rates and zero foreign material—a step too often skipped by repackagers or bulk traders. True DC Grade should run on a rotary press without extra step-ups in diluents or binders, even with relatively high vitamin content. Formulators we supply tell us they can swap out 1:1 with control lots and hit all their process checks the first time—something we could only guarantee by controlling every stage from synthesis through to packing.
Fortifying foods or developing nutritional supplements puts unique stress on every ingredient. For thiamine HCl, food processors worry about stability in premixes, ease of blending with flour or ready-to-eat products, and absence of strange aftertaste or visible speckling. Traditional thiamine grades sometimes clump in oil-based premixes or fail to disperse evenly in low-moisture cereals.
We manufacture our DC Grade thiamine hydrochloride with these applications in mind. The product’s improved flow and reduced caking mean fewer issues at the blending and packing stages, allowing fortification plants to keep high-speed ribbon blenders and packing lines online with fewer stops to clear clogged feeders. Repeated QC reports from multinational food manufacturers—who process hundreds of tons per week—show that our DC grade keeps batch homogeneity within narrow margins and resists deliquescence in humid environments.
Nutrition houses using our DC Grade in effervescent formulations, chewables, or vitamin blends report that the product’s texture and rapid wetting give a cleaner dissolve and allow for higher loadings without slumping or sticking. Our technical team works with customers to trial lots in R&D scale, then supports trouble-shooting during scale-up to full industrial operations. Government fortification schemes, especially where dosing precision by law is critical, benefit from a DC Grade unlikely to drift in density or particle size from lot to lot.
Medicine manufacturers handle thiamine hydrochloride under stricter regulatory scrutiny, expecting low batch-to-batch variance and traceable GMP records. Our tablets have been used for global markets: prescription-grade vitamin B1 therapies, over-the-counter supplements, and special medical foods. A pharmaceutical plant manager once told us, “If it flows, it runs. If it runs, it works.” For them, our DC Grade eliminates the need for additional flow agents or blending intermediates—removing points of cross-contamination and validation headache.
Quality and compliance teams tour our facility expecting not just documentation, but living proof of traceability—from original raw material acquisition through finished product packing. Our DC Grade runs on validated lines, with locked-down change controls for every process modification. Stability testing under ICH conditions, heavy metals screening with ICP-MS, and tight microbial checks all form part of routine batch release. Only robust control at every stage delivers tablets or capsules that meet the strictest pharmacopeia requirements.
Some formulators ask, “Isn’t all thiamine HCl the same?” Experience shows otherwise. Factors like particle size, granule cohesion, and response to ambient humidity drastically change whether batches pass or fail in the tableting room. Direct compression grade isn’t made by simply sieving or milling; it takes engineered granules and binder technology. Our process removes fines, optimizes surface characteristics, and aims not for average performance but for repeatability across every shift.
Real feedback counts more than theoretical comparisons. Factories using bulk thiamine from traders commonly make up losses by overdosing or adding rework steps into their process. With our DC Grade, clients report waste reduction, higher throughput, and fewer complaints from end users. We invest in on-site support, helping customers optimize formulations, and, when batch hiccups do occur, our technical team troubleshoots with real-world experience, not just standard answers.
In the last decade, demand for direct compression nutrients has increased as industry targets faster production speeds, increased compliance, and fewer touchpoints in plant processes. We stay in close contact with lead mechanics, QA, and R&D specialists at customer firms, who rarely mince words about what works and what doesn’t. One of the main drivers behind our DC Grade was their push for reliable, low-dust materials matching the speed and precision of state-of-the-art continuous tableting lines—a challenge that comes from working side-by-side, not from behind a sales desk.
Ongoing feedback led us to refine our product every year. A decade ago, no one asked about lubricity or particle breakage under high tooling speed; now, these are standard QC discussions. By taking time in our own pilot tableting lab to mimic full-scale batch runs, we have sidestepped many common pitfalls before product even leaves our warehouse. This experience-in-practice approach is critical not only for regulatory approval but for real efficiency at the tablet press or food blender.
Looking ahead, customer plants ask for ingredients that reduce operator intervention, cleaning time, and wasted product. Sustainability pressures—reducing fugitive dust, energy for rework, water use in cleaning—are met directly by ingredient engineering, not by after-the-fact fixes. Our thiamine hydrochloride DC grade joins a portfolio reshaped by these needs; every new lot update or equipment upgrade is driven by conversations with actual line users, not by third-party resellers.
Whether making high-potency single vitamin tablets or complex multivitamin blends, achieving every expected performance attribute requires close partnership between raw material manufacturer and line operator. We do not rest on standard specs; we run thousands of tableting and blending sequences in our own lab and listen to every claim, good or bad, from our customers’ production teams. That’s where real improvements happen—on the line, with real consequences in output and consistency.
Manufacturing and delivering thiamine hydrochloride DC Grade requires more than meeting purity claims; it demands deep understanding of every process step from synthesis through finished dosage. Coming from the production floor, we know that caked bins, inconsistent flow, or press slowdowns dominate daily plant reality more than any spec sheet. Building our DC Grade means we answer every technical question not with marketing, but with practice, trial, and direct input from those handling tons of material.
We have watched process improvements ripple across everything from operator safety (less airborne dust) to management’s bottom line (less downtime, lower overages, more reliable audits). Our commitment draws not from distant QA offices, but from daily hands-on verification and continuous dialogue with production teams worldwide. Every innovation, whether in particle design or logistics, comes as a response to something learned during hands-on troubleshooting on the customer’s line.
The push toward direct compression vitamins gains pace as manufacturers try to trim steps, cut waste, and tighten regulatory compliance. We see every new project as not just a transaction, but a partnership: one built from a shared need to make real, useful improvements in plant reliability and output. Each year brings new technical demands, tighter customer specs, and unexpected challenges. Only a manufacturer working closely with production and formulation teams gains the know-how to deliver not just a commodity, but a true solution.
Our story with thiamine hydrochloride DC Grade continues to evolve. We keep learning from every tablet, every feedback session, and every bottle that makes it from our line to yours. As a manufacturer who spends as much time on the line as in the office, we take pride in offering a product built by experience and improved by real-world results, shipment after shipment.